This Collection: | Timeline | Search/Browse | Contributors | Permissions | Help | HOME

Cholera Epidemics in the 19th Century

The Great Plague of London, 1665

The Boston Smallpox Epidemic, 1721

“Pestilence” and the Printed Books of the Late 15th Century

Spanish Influenza in North America, 1918–1919

Syphilis, 1494–1923

Tropical Diseases and the Construction of the Panama Canal, 1904–1914

Tuberculosis in Europe and North America, 1800–1922

The Yellow Fever Epidemic in Philadelphia, 1793

General Materials

Notable People

Related Links


Cholera Epidemics in the 19th Century

The prevention and treatment of epidemic cholera: and its true pathological nature, in a series of letters. Cleveland: M.C. Younglove & Co., 1849. From the holdings of Andover–Harvard Theological Library—Harvard Divinity School
The Prevention and Treatment of Epidemic Cholera. From the holdings of Andover–Harvard Theological Library—Harvard Divinity School.

First appearing in Europe and North America beginning in 1831–1832 and presumed to have come from India, epidemic cholera returned and traveled around the world many times through the end of the century, killing many thousands. Causing profuse and violent cramps, vomiting and diarrhea, with dehydration so rapid and severe the blood thickens and the skin becomes deathlike and blue, cholera victims can die in a matter of hours. Because 19th-century transformations in industrial, urban, political, and cultural life were intimately connected with discussions of proper public health practices and causes of disease, attempts to explain epidemic cholera involved every part of society.

Causes of Cholera

For much of the century, most European and American physicians believed cholera was a locally produced miasmatic disease—an illness brought about by direct exposure to the products of filth and decay. Climate and geographic location were also factors. It was a common assumption that those who engaged in morally and physically intemperate behavior or who had inferior cultural practices were more likely to get cholera when exposed to these miasmas and environmental conditions. Observations that the poor, who lived in densely populated urban slums, suffered from cholera in greater numbers than the rich, who were much differently housed, were used as evidence for this assertion. The germ theory, developed in the later 19th century, placed less emphasis on social and environmental factors, although the issue of individual predisposition and susceptibility due to personal behavior lingered.

Was Cholera Contagious?

For most of the 19th century, most scientists, physicians and sophisticated lay people believed cholera was not contagious. The observation that a doctor could have daily contact with cholera patients without falling ill led to the conclusions that cholera was not transmitted from person to person. This was an accurate observation given that cholera is usually transmitted through contaminated drinking water, as John Snow first demonstrated in 1855.

Until Robert Koch identified the cholera bacillus in 1883, science continued to favor anticontagionism. Leading anticontagionists or contingent contagionists included Max von Pettenkofer and Southwood Smith. According to the contingent contagionist perspective, cholera could be contagious, but only under particular circumstances.

The existence of the cholera bacillus did not necessarily prove cholera’s contagiousness either; some argued that the bacillus was the product of the disease, not its cause. Another issue was how to explain the existence of healthy carriers—people who had the cholera bacillus in their bodies but who were not sick. In practice, public health measures often involved a blend of contagionist and anticontagionist views.

The International Sanitary Conferences, predecessor to the World Health Organization, were first convened in Paris in 1851 to discuss cholera’s contagiousness; Europe’s most important scientists and public health officials attended the meetings. Quarantine, intimately related to contagion, was another important topic at the Conferences, since it was of central concern to government officials and those involved in commerce. For if cholera was not contagious, there was no reason to submit to the significant personal and economic sacrifices involved in quarantines.

19th–Century Treatments

Despite the continued discussion about the cause of cholera, over the course of the 19th century the actual treatment of the disease did not change much. Patients with families were cared for at home. Physicians, when called, would use such characteristic treatments as bleeding or opium. Homeopathic methods were popular among the middle and upper classes, as were other eclectic treatments, and all manner of dietary and hygienic regimens were promoted in newspapers and books. Those without families might find themselves in charity hospitals, which could become grim places indeed during an epidemic. Preachers gave sermons on the meaning of cholera for both individuals and society. Riots ensued due to popular revolt against mass burials.

The Epidemics Subside

By the end of the 19th century, cholera epidemics no longer appeared in Europe and North America. The reasons for this are uncertain, but standards of living had risen and many communities had made major changes in sanitation practices and established permanent boards of health. As part of the transformation to the germ theory, medical thought had changed in many ways as well. In 1831, most physicians believed cholera to be a nonspecific, noncontagious miasmatic condition that favored the morally and physically predisposed. By the end of the 19th century, although the miasmatic interpretation still had influence, cholera was primarily understood to be a specific contagious disease caused by a particular microscopic organism.


Selected Contagion Resources

This is a partial list of digitized materials available in Contagion: Historical Views of Diseases and Epidemics. For additional materials on the topic “Cholera Epidemics in the 19th Century,” click here or search the collection’s Catalog and Full Text databases.

Web Pages

Concepts of Contagion and Epidemics
Humoral Theory
Germ Theory
International Sanitary Conferences
James Jackson, 1777–1867
Robert Koch, 1843–1910
Medical Geography
Florence Nightingale, 1820–1910
Public Health
Rudolf Virchow, 1821–1902
Max von Pettenkofer, 1818–1901


Papers of Samuel Leonard Abbot, 1867.
Papers of James Jackson, 1800–1867.
Papers of Abel Lawrence Peirson, 1812–1905.
Report (manuscript) by Charles Douglass Cleaveland, Apr. 1, 1867. B MS c604.4.
Reports, questionnaire, abstracts, etc. of the Massachusetts Medical Society, Suffolk District Medical Society, Committee to Consider Cases of Cholera, [1867], B MS c604.2.


Causes of Cholera

An Account of the Rise and Progress of the Indian or Spasmodic Cholera: With a Particular Description of the Symptoms Attending the Disease: Illustrated by a Map, Showing the Route and Progress of the Disease, from Jessore, Near the Ganges, in 1817, to Great Britain, in 1831. New Haven: L.H. Young, 1832.
Broussais, F.J.V. Le Choléra Morbus Epidemique: Observé et Traité Selon la Méthode Physiologique. Paris: Mademoiselle Delaunay, 1832.
Dewey, Orville. A Sermon on the Moral Uses of the Pestilence, Denominated Asiatic Cholera: Delivered on Fast-Day, August 9, 1832. New Bedford?: 1832.
Hawkins, Francis Bisset. History of the Epidemic Spasmodic Cholera of Russia: Including a Copious Account of the Disease Which Has Prevailed in India, and Which Has Travelled, Under That Name, from Asia into Europe, Illustrated by Numerous Official and Other Documents, Explanatory of the Nature, Treatment, and Prevention of the Malady. London: J. Murray, 1831.
Koch, Robert Wasserfiltration und Cholera. Leipzig: Veit, 1893.

Was Cholera Contagious?

Epidemic Cholera: Its Mission and Mystery, Haunts and Havocs, Pathology and Treatment: With Remarks on the Question of Contagion, the Influence of Fear, and Hurried and Delayed Interments. New York: Carleton, 1866.
Great Britain. Report on Quarantine. London: Printed by W. Clowes & Sons for H.M.S.O., 1849.
Pettenkofer, Max von. Zur Frage über die Verbreitungsart der Cholera: Entgegnungen und Erläuterungen zu seiner Schrift “Ueber die Verbreitungsart der Cholera.” München: Cotta, 1855
Pettenkofer, Max von. Cholera: How to Prevent and Resist It. London: Baillière, Tindall, & Cox, 1883.
Snow, John. Snow on Cholera: Being a Reprint of Two Papers. New York: The Commonwealth Fund; London: H. Milford, Oxford University Press, 1936.

19th-Century Treatments

Graham, Sylvester. A Lecture on Epidemic Diseases Generally, and Particularly the Spasmodic Cholera: Delivered in the City of New York, March, 1832, and Repeated June, 1832, and in Albany, July 4, 1832, and in New York, June, 1833: With an Appendix, Containing Several Testimonials, and a Review of Beaumont's Experiments on the Gastric Juice. Boston: David Cambell, 1838.
Hawthorne, George Stewart. The Prevention and Treatment of Epidemic Cholera: and Its True Pathological Nature, in a Series of Letters. Cleveland: M.C. Younglove & Co., 1849.
Holt, Daniel. Cholera and Its Homœopathic Treatment: With an Account of Its Success in Europe, and America, and Remarks Upon Its Symptoms, Preventive Means, Early Management, &c, &c Lowell: B.H. Penhallow, printer, 1849.
Shew, Joel. The Cholera, Its Causes, Prevention, and Cure: Showing the Inefficacy of Drug-Treatment, and the Superiority of the Water-Cure, in This Disease. New York: Fowlers and Wells, 1849.
Whittle, Ewing. The Symptomatic Treatment of Asiatic Cholera. London: John Churchill, 1850.


The following sources were used in writing this page.

Ackerknecht, Erwin H. “Anticontagionism Between 1821 and 1867.” Bulletin of the History of Medicine 22 (1948): 562–593.
Arnold, David. “Cholera and Colonialism in British India.” Past and Present, No. 113 (Nov., 1986), pp. 118-151.
Baldwin, Peter. Contagion and the State in Europe, 1830-1930. Cambridge: Cambridge University Press, 1999.
Briggs, Asa. “Cholera and Society in the Nineteenth Century.” Past and Present, No. 19 (Apr., 1961), pp. 76-96.
Delaporte, Francois, trans. Arthur Goldhammer. Disease and Civilization: The Cholera in Paris, 1832. Cambridge, MA, and London: MIT Press, 1986.
Evans, Richard. Death in Hamburg: Society and Politics in the Cholera Years, 1830-1910. Oxford: Clarendon Press, 1987.
Frieden, Nancy. “The Russian Cholera Epidemic, 1892–93, and Medical Professionalization.” Journal of Social History, Vol. 10, No. 4 (Summer, 1977), pp. 538-559.
Howard-Jones, Norman. The Scientific Background of the International Sanitary Conferences, 1851–1938. Geneva: World Health Organization, 1975.
Leiker, James and Powers, Ramon. “Cholera Among the Plains Indians: Perceptions, Causes, Consequences.” The Western Historical Quarterly, Vol. 29, No. 3 (Autumn, 1998), pp. 317-340.
Pelling, Margaret. Cholera, Fever and English Medicine, 1825–1865. Oxford and New York: Oxford University Press, 1978.
Rosenberg, Charles E. The Cholera Years: The United States in 1832, 1849, and 1866. University of Chicago Press: Chicago and London, 1962, 1987.
Rosenberg, Charles E. Explaining Epidemics and Other Studies in the History of Medicine. Cambridge: Cambridge University Press, 1992.


OCP Home | Selection of Web–Accessible Collections | HOLLIS | Harvard Libraries | Harvard Home | Contact | ©2018 The President and Fellows of Harvard College